Two Electrode Voltage Clamp (Oocyte) Systems

These systems are designed for two-electrode, whole-cell voltage clamping of large cells such as Xenopus oocytes and cell structures such as squid axons. They are either bundled with an Oocyte Clamp Amplifier or a more comprehensive Two Electrode Voltage Clamp Workstation, which provide clamping and amplification of measured signals from glass microelectrodes/sharp electrodes. The amplified signals are then recorded and analysed via the supplied PowerLab and LabChart Pro data acquisition system. Glass microelectrodes/sharp electrodes are purchased separately. Two E series electrode holders are also supplied to connect 1.5 mm diameter glass microelectrodes/sharp electrodes to the corresponding headstages of the Oocyte Clamp Amplifier. Their vented designs prevent pressure build-up inside the electrode, which can damage oocytes.

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Accessories (optional and purchased separately):

Configurations

Oocyte Clamp System

PL3508B75-V

Designed for two-electrode, whole-cell voltage clamping of large cells such as Xenopus oocytes and cell structures such as squid axons. It includes:

Two Electrode Voltage Clamp Workstation System

PL3508B76-V

A comprehensive system with typical components for research involving Oocytes. It includes:

Features

  • High compliance voltage (±180 V).
  • Unique bath clamp circuitry.
  • Ideal for clamping large cells and cell structures, e.g. squid axons.
  • Extended current measuring range.
  • Decreased noise level and 4-pole Bessel filter.
  • An internal switch permits measurements of the current in series with the current electrode, instead of in the bath.
  • Optional differential voltage headstages.
  • Buzz controls (1 kHz square wave) for each electrode aid in penetration of cell membranes with a minimum of leakage.
  • Overload alarm (audible and visual) indicate when the compliance voltage is exceeded safeguarding the Oocyte and indicating that current records are subject to saturation.
  • DC Offsets for both voltage and current electrodes.
  • Electrode Test for both electrodes.
  • Capacity Compensation for the Vm voltage input.

Technical

When ordering please specify mains voltage power; where V = 115 for 115-120 V, and where V = 220 for 220-240 V.

Product Codes

PL3508B75-V
Oocyte Clamp System
 
PL3508B76-V

Two Electrode Voltage Clamp Workstation System